Hereditary cerebral cavernous angiomas: clinical and genetic features in 57 French families

@article{Labauge1998HereditaryCC,
  title={Hereditary cerebral cavernous angiomas: clinical and genetic features in 57 French families},
  author={Pierre Labauge and Sophie S Laberge and Laurent Brunereau and Claude L{\'e}vy and Elizabeth Tournier-Lasserve},
  journal={The Lancet},
  year={1998},
  volume={352},
  pages={1892-1897}
}
BACKGROUND Cavernous angiomas, which are vascular malformations mostly located in the central nervous system, may be inherited as an autosomal dominant disorder known as familial cerebral cavernoma (FCC). FCC has been studied in Hispanoamerican families, in which a strong founder effect was shown. We studied the families of 57 non-Hispanic patients with cavernous angiomas. METHODS All 28 neurosurgery centres in France collaborated in the study. Inclusion criteria were: families of index… CONTINUE READING
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