Hereditary canine spinal muscular atrophy.

  title={Hereditary canine spinal muscular atrophy.},
  author={Linda Collins Cork and John Wesley Griffin and John F. Munnell and Michael D Lorenz and Robert J. Adams},
  journal={Journal of neuropathology and experimental neurology},
  volume={38 3},
Hereditary canine spinal muscular atrophy is a newly recognized motor neuron disease occurring in Brittany Spaniels. The clinical manifestations, pattern of inheritance, electrodiagnostic findings, and muscle biopsies have features in common with human spinal muscular atrophy. Neuropathological examination discloses some loss of motor neurons in the spinal cord and brainstem. Many of the surviving motor neurons have neurofibrillary swellings in proximal axons, an abnormality similar to that… CONTINUE READING


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