Hereditary cancer syndromes.

  title={Hereditary cancer syndromes.},
  author={Thomas S. Frank},
  journal={Archives of pathology & laboratory medicine},
  volume={125 1},
  • Thomas S. Frank
  • Published 2001 in Archives of pathology & laboratory medicine
OBJECTIVE To summarize the biological basis, clinical implications, identification, and medical management of syndromes associated with increased risk of common adult cancers. DATA SOURCES Recent studies and data available from molecular and clinical analysis of genes responsible for autosomal-dominant inheritance of cancer risk. DATA SYNTHESIS Several hereditary cancer syndromes have been identified for which there are increasingly effective diagnostic and management options. Specific… CONTINUE READING
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