Hereditary and acquired complement dysregulation in membranoproliferative glomerulonephritis.

@article{Licht2009HereditaryAA,
  title={Hereditary and acquired complement dysregulation in membranoproliferative glomerulonephritis.},
  author={Christoph Licht and V{\'e}ronique Fr{\'e}meaux-Bacchi},
  journal={Thrombosis and haemostasis},
  year={2009},
  volume={101 2},
  pages={
          271-8
        }
}
Membranoproliferative glomerulonephritis (MPGN) is a chronic progressive renal disease that is diagnosed on the basis of renal histological features. Several MPGN subtypes have been defined by the localization and composition of glomerular deposits (electron dense, Ig and C3). MPGN II or dense deposit disease (DDD) which is defined by the occurrence of electron dense deposits within the lamina densa of the glomerular basement membrane (GBM) is strongly associated with dysregulation of the… CONTINUE READING

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