Herbicides to curb human parasitic infections: in vitro and in vivo effects of trifluralin on the trypanosomatid protozoans.

@article{Chan1993HerbicidesTC,
  title={Herbicides to curb human parasitic infections: in vitro and in vivo effects of trifluralin on the trypanosomatid protozoans.},
  author={Marion M Chan and Max Grogl and Clark C Chen and E J Bienen and Dunne Fong},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 12},
  pages={5657-61}
}
Leishmaniasis is a major tropical disease for which current chemotherapies, pentavalent antimonials, are inadequate and cause severe side effects. It has been reported that trifluralin, a microtubule-disrupting herbicide, is inhibitory to Leishmania amazonensis. In this study, the in vitro effect of trifluralin on different species of trypanosomatid… CONTINUE READING