Herbal medicines and postoperative haemorrhage

  title={Herbal medicines and postoperative haemorrhage},
  author={Narlaka Jayasekera and Arif Ali Baig Moghal and Fadhil Kashif and Lakshman Delgoda Karalliedde},
A 65-year-old man with gross osteoarthritis of the left hip was prepared for elective total hip arthroplasty. He had a history of chronic obstructive pulmonary disease, early Alzheimer’s dementia and adenocarcinoma of the prostate. He was on oral diclofenac sodium, intramuscular goserelin acetate and a brown liquid herbal medicine (one tablespoon twice a day). At pre-operative assessment the patient was advised to discontinue the herbal and non-steroidal anti-inflammatory medicine 2 weeks prior… 
Potential effects of herbal medicines and nutritional supplements on coagulation in ENT practice
When encountering patients presenting with epistaxis, or in the elective surgical setting, a thorough enquiry about the use of herbal medicines is of great importance, so as to emphasise their individual importance.
The Effect of Herbal Medicines on Platelet Function: An In Vivo Experiment and Review of the Literature
Neither this experiment nor a review of the literature supports the concern of perioperative bleeding in users of commonly used herbal medicines, because the herbal medicines investigated in this study do not affect platelet function in vivo.
Risk of hemorrhage associated with co-prescriptions for Ginkgo biloba and antiplatelet or anticoagulant drugs.
Although the combination of G. biloba extract with antiplatelet or anticoagulants showed insignificant correlation to the risk of hemorrhage, patients using ginkgo, particularly those with known bleeding risks and elderly, should take a particular attention to the possibility of increasing risk of bleeding.
Management of coagulopathy in the setting of acute neurosurgical disease and injury
Common causes of coagulopathy, as well as its management in acute neurosurgical settings, are outlined in this review.
Potential interaction of Ginkgo biloba leaf with antiplatelet or anticoagulant drugs: what is the evidence?
  • K. Bone
  • Biology
    Molecular nutrition & food research
  • 2008
Control studies consistently indicate that Ginkgo does not significantly impact haemostasis nor adversely affect the safety of coadministered aspirin or warfarin, and there is scant information from case reports or controlled trials to support the suggestion that Ginkinggo potentiates the effects of anticoagulant or antiplatelet drugs.
Interactions Between Herbal Medicines and Prescribed Drugs
Numerous interactions between herbal medicines and conventional drugs have been documented, while the significance of many interactions is uncertain, several interactions, particularly those with St John’s wort, may have serious clinical consequences.
Dietary supplement interactions with medications used commonly in dentistry.
The authors address the interactions of greatest clinical concern with a high-quality evidence-based foundation in either randomized controlled clinical trials or meta-analyses.
State of the Art Review: Pharmacists' Approach to Selecting Dietary/Nutritional Supplements for Patients
An evidence-based approach to selecting dietary supplements is discussed, including the laws surrounding these products, professional organizations' position statements, con- cerns with use, special populations, quality control programs, and reliable databases/information resources to aid in selection.
ADME of Herbal Dietary Supplements
This chapter provides a review of the potential for herb–drug interactions based on literature reports for those herbs that are most popularly used in the United States and relevant clinical and human in vitro studies that have evaluated metabolism-based or absorption-based mechanisms to understand the interactions between these herbs and commonly used drugs.


The peri‐operative implications of herbal medicines
An increasing number of patients are taking herbal medicines such as echinacea, garlic, ginkgo biloba, ginseng, St John's Wort, valerian, ephedra, kava, grapefruit juice and ginger, which may have some benefits, but adverse effects such as increased bleeding tendencies and drug interactions are associated with their use.
A case of cerebral haemorrhage—can Ginkgo biloba be implicated?
The case of a 56 year old man who suffered a spontaneous intracerebral haemorrhage after regular self medication with the herbal preparation, Ginkgo biloba leaf extract is described, and the possible
Retrobulbar haemorrhage associated with chronic Gingko biloba ingestion
A case is reported of a woman who developed this complication and was subsequently found to have been taking Gingko biloba extract tablets which may have predisposed her to developing the haemorrhage.
Safety issues in herbal medicine: implications for the health professions
It may be necessary to develop a separate database to promote adverse drug reaction reporting for herbal medicine and the wider field of complementary and alternative medicine.
The LMA 'ProSeal'--a laryngeal mask with an oesophageal vent.
A preliminary crossover comparison with the standard mask in 30 adult female patients showed no differences in insertion, trauma or quality of airway, and it is concluded that the new device merits further study.
Hyphéma spontané provoqué par l'extrait de Ginkgo biloba
L'histoire, les donnees cliniques et paracliniques, ainsi que les elements biologiques suggerent fortement that le Ginkgo biloba ait pu causer la survenue de l'hyphema spontane meme dans l'absence of tout autre facteur predisposant.