Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase

Abstract

Urokinase (uPA) and its receptor (uPAR) play an important role in tumour growth and metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. Targeting the excessive activation of this system as well as the proliferation of the tumour vascular endothelial cell would be expected to prevent… (More)
DOI: 10.1186/1476-4598-12-54

Topics

8 Figures and Tables

Slides referencing similar topics