Her2 expression and gene amplification is rarely detectable in patients with oral squamous cell carcinomas.

Abstract

PURPOSE Her2 (ErbB2) transforms cells when overexpressed and is an important therapeutic target in breast cancer. Contrary to breast cancer, studies on Her2 overexpression and gene amplification in squamous cell carcinomas of the head and neck region described largely different results. This study was undertaken to learn more on the prevalence and clinical… (More)
DOI: 10.1111/jop.12173

Topics

6 Figures and Tables

Cite this paper

@article{Hanken2014Her2EA, title={Her2 expression and gene amplification is rarely detectable in patients with oral squamous cell carcinomas.}, author={Henning Hanken and Robert Gaudin and Alexander Gr{\"o}be and Meike Fraederich and Wolfgang Eichhorn and Ralf Smeets and Ronald Simon and Guido Sauter and Katharina Grupp and Jacob Robert Izbicki and Susanne Sehner and Max Heiland and Marco Blessmann}, journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology}, year={2014}, volume={43 4}, pages={304-8} }