Her-2/neu oncogene amplification and protein over-expression in interval and screen-detected breast cancers.

@article{Anttinen2003Her2neuOA,
  title={Her-2/neu oncogene amplification and protein over-expression in interval and screen-detected breast cancers.},
  author={Jorma Anttinen and Teijo Kuopio and Marjukka Nykanen and Helena Torkkeli and Urpo Saari and Matti T Juhola},
  journal={Anticancer research},
  year={2003},
  volume={23 5b},
  pages={4213-8}
}
BACKGROUND Studies of Her-2/neu protein expression in interval and screen-detected breast cancers have been conflicting. Therefore we assessed the Her-2/neu amplification status in these groups by using in situ hybridization. PATIENTS AND METHODS The Her-2/neu oncogene amplification and protein over-expression were compared in 79 screen-detected and 39 interval breast carcinomas, using a novel and well-documented chromogenic in situ hybridization (CISH) method and immuhistochemistry… CONTINUE READING
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