Her-2/neu expression in breast cancer--A comparison of different diagnostic methods.

  title={Her-2/neu expression in breast cancer--A comparison of different diagnostic methods.},
  author={Peter Benoehr and Verena Henkel and Runa Speer and Ulrich Vogel and Karl Sotlar and Babur Aydeniz and Arnulf Reiser and Hans J Neubauer and Karim Tabiti and Diethelm Wallwiener and Susan E. Clare and Raffael Kurek},
  journal={Anticancer research},
  volume={25 3B},
BACKGROUND Determination of Her-2/neu overexpression in breast cancer has previously been shown to be of prognostic significance. In this study, Her-2/neu expression in breast cancer was characterised by real-time PCR (RLT-PCR) based LightCycler-HER-2/neu DNA Quantification with immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH). MATERIAL AND METHODS Fifteen specimens of invasive breast cancer - whole tissue sections as well as microdissected tumour cells - were… CONTINUE READING
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