Heptose Sounds the Alarm: Innate Sensing of a Bacterial Sugar Stimulates Immunity

Abstract

The first line of defense against infection, the innate immune system, identifies and responds to microbial threats. Central to this response is the discrimination of self from non-self. Pattern recognition receptors (PRRs) expressed by mammalian cells detect molecular signatures unique to microbes yet absent from the host. These molecules, termed pathogen… (More)
DOI: 10.1371/journal.ppat.1005807

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Cite this paper

@inproceedings{Gaudet2016HeptoseST, title={Heptose Sounds the Alarm: Innate Sensing of a Bacterial Sugar Stimulates Immunity}, author={Ryan G Gaudet and Scott D Gray-Owen}, booktitle={PLoS pathogens}, year={2016} }