Heptakis(6-amino-6-deoxy)-beta-cyclodextrin as a chiral selector for the separation of anionic analyte enantiomers by capillary electrophoresis.

@article{Budanova2004Heptakis6amino6deoxybetacyclodext,
  title={Heptakis(6-amino-6-deoxy)-beta-cyclodextrin as a chiral selector for the separation of anionic analyte enantiomers by capillary electrophoresis.},
  author={Natalia Budanova and Elena N Shapovalova and Sergei Lopatin and Valery Varlamov and Oleg A Shpigun},
  journal={Electrophoresis},
  year={2004},
  volume={25 16},
  pages={2795-800}
}
A hepta-substituted beta-cyclodextrin bearing seven amino groups, heptakis(6-amino-6-deoxy)-beta-cyclodextrin (per-6-NH2-beta-CD) was successfully used as a chiral selector for the enantioseparation of different anionic analytes. The running buffer pH and chiral selector concentration were the studied parameters crucial in achieving the maximum possible enantioresolution. Enantiomeric separation of a mixture of seven carboxybenzyl-amino acids was achieved in 24 min. Excellent resolution was… CONTINUE READING