Hepsin and maspin are inversely expressed in laser capture microdissectioned prostate cancer.

@article{Chen2003HepsinAM,
  title={Hepsin and maspin are inversely expressed in laser capture microdissectioned prostate cancer.},
  author={Zuxiong Chen and Zhenbin Fan and John E. McNeal and Rosalie Nolley and Mitchell C Caldwell and Mamatha Mahadevappa and Zhaomei Zhang and J. Anthony Warrington and Thomas A. Stamey},
  journal={The Journal of urology},
  year={2003},
  volume={169 4},
  pages={1316-9}
}
PURPOSE Recent studies have shown that hepsin, a serine protease, is over expressed in prostate cancers, implicating hepsin activity in tumor invasion. Using microarray technology we have previously identified 22 genes that were up-regulated in high grade prostate cancers compared with benign prostatic hyperplasia. Of them hepsin was the most differentially over expressed. In the current report we compare hepsin to maspin (BD Transduction Laboratories, San Diego, California), a serine protease… CONTINUE READING

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