Hepcidin modulation in human diseases: from research to clinic.

  title={Hepcidin modulation in human diseases: from research to clinic.},
  author={Alberto Piperno and Raffaella Mariani and Paola Trombini and Domenico Girelli},
  journal={World journal of gastroenterology},
  volume={15 5},
By modulating hepcidin production, an organism controls intestinal iron absorption, iron uptake and mobilization from stores to meet body iron need. In recent years there has been important advancement in our knowledge of hepcidin regulation that also has implications for understanding the physiopathology of some human disorders. Since the discovery of hepcidin and the demonstration of its pivotal role in iron homeostasis, there has been a substantial interest in developing a reliable assay of… CONTINUE READING

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