Hepcidin in Anemia and Inflammation in Chronic Kidney Disease

@article{Mayszko2007HepcidinIA,
  title={Hepcidin in Anemia and Inflammation in Chronic Kidney Disease},
  author={J. Małyszko and M. Myśliwiec},
  journal={Kidney and Blood Pressure Research},
  year={2007},
  volume={30},
  pages={15 - 30}
}
Maintaining the correct iron balance is crucial for health. Our understanding of the molecular control of iron metabolism has increased dramatically over the past 5 years due to the discovery of hepcidin. This is a circulating antimicrobial peptide mainly synthesized in the liver, which has been recently proposed as a factor regulating the uptake of dietary iron and its mobilization from macrophages and hepatic stores. Inflammation causes an increase of production of hepcidin, which is a potent… Expand
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TLDR
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SERUM HEPCIDIN LEVELS IN ANEMIA OF CHRONIC KIDNEY DISEASES COMPARED TO IRON DEFICIENCY ANEMIA AND IT'S CORRELATION WITH SERUM LEVELS OF HS –C REACTIVE PROTEIN, INTERLUKIN-6 AND FERRITIN
Hepcidin, is a recently discovered small peptide secreted by the liver to act as a key regulator of iron homeostasis. Patients on hemodialysis(HD) are usually anemic ,because of defectiveExpand
Serum prohepcidin level in children with chronic kidney disease in relation to iron markers
TLDR
There is a positive association between serum prohepcidin level and serum ferritin and other conventional markers of iron metabolism in CKD patients, with close analysis of data to different hematological parameters, especially iron markers. Expand
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