Hepatotropism of GB virus C (GBV-C): GBV-C replication in human hepatocytes and cells of human hepatoma cell lines.

@article{Seipp1999HepatotropismOG,
  title={Hepatotropism of GB virus C (GBV-C): GBV-C replication in human hepatocytes and cells of human hepatoma cell lines.},
  author={Stefanie Seipp and M Scheidel and Walter J. Hofmann and Ulrich Toex and Lorenz Theilmann and Tobias Goeser and Birgit Kallinowski},
  journal={Journal of hepatology},
  year={1999},
  volume={30 4},
  pages={570-9}
}
BACKGROUND/AIMS Recently, GB virus C (GBV-C) has been identified as another virus potentially causing viral hepatitis. However, its hepatotropism and pattern of infection in humans is still unknown. To elucidate the presence and replication of GBV-C in the human liver, we investigated tissue samples of six explanted livers from five GBV-C mono- or GBV-C/HCV co-infected patients for GBV-C RNA plus- and minus-strand RNA. METHODS These tissues were examined using nested RT-PCR followed by… CONTINUE READING

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