Corpus ID: 24216633

Hepatotoxicity of carbon tetrachloride: protective effect of Gongronema latifolium.

@article{Etim2008HepatotoxicityOC,
  title={Hepatotoxicity of carbon tetrachloride: protective effect of Gongronema latifolium.},
  author={O. E. Etim and E. Akpan and I. F. Usoh},
  journal={Pakistan journal of pharmaceutical sciences},
  year={2008},
  volume={21 3},
  pages={
          268-74
        }
}
The protective effect of the ethanolic extract of Gongronema latifolium (GLE) on carbon tetrachloride (CCI4) induced hepatic toxicity was studied. Liver enzymes studied included alanine aminotransferase (ALT), aspartate aminotraferase (AST), and alkaline phosphates (ALP). Hepatic injuries involved with possible necrosis which may have contributed to its possible pathogenesis was explored. Administration of toxicant only showed that the ALT level was significantly (P<0.05) increased to 345.83… Expand
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