Hepatotoxicity of anti-inflammatory and analgesic drugs: ultrastructural aspects

@article{Manov2006HepatotoxicityOA,
  title={Hepatotoxicity of anti-inflammatory and analgesic drugs: ultrastructural aspects},
  author={Irena Manov and Helen Motanis and Idan Frumin and Theodore C. Iancu},
  journal={Acta Pharmacologica Sinica},
  year={2006},
  volume={27},
  pages={259-272}
}
AbstractWith the increasing incidence of drug-induced liver disease, attempts are being made to better understand the mechanisms behind these frequently life-endangering reactions. Analgesics and anti-inflammatory drugs are a major group exhibiting hepatotoxicity. We review research relating to these reactions, focusing on ultrastructural findings, which may contribute to the comprehension and possible avoidance of drug-induced liver disease. We also present some original observations on… Expand
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