Hepatotoxic potency of various chlorinated hydrocarbon vapours relative to their narcotic and lethal potencies in mice.

@article{Gehring1968HepatotoxicPO,
  title={Hepatotoxic potency of various chlorinated hydrocarbon vapours relative to their narcotic and lethal potencies in mice.},
  author={Perry J. Gehring},
  journal={Toxicology and applied pharmacology},
  year={1968},
  volume={13 3},
  pages={
          287-98
        }
}
  • Perry J. Gehring
  • Published in
    Toxicology and applied…
    1968
  • Chemistry, Medicine
  • Abstract Hepatic damage was determined in mice by serum glutamic-pyruvic transaminase (SGPT) activity 24 hours following single exposures to the vapor concentrations of carbon tetrachloride, chloroform, 1,1,2-trichloroethane, tetrachloroethylene, trichloroethylene, dichloromethane, and 1,1,1-trichloroethane expected to kill 50% of the animals in 9–12 hours of continuous exposure. A median effective exposure duration for an increase in SGPT activity was calculated and expressed as a ratio of the… CONTINUE READING

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