Hepatosplenic gammadelta T-cell lymphoma is a rare clinicopathologic entity with poor outcome: report on a series of 21 patients.

@article{Belhadj2003HepatosplenicGT,
  title={Hepatosplenic gammadelta T-cell lymphoma is a rare clinicopathologic entity with poor outcome: report on a series of 21 patients.},
  author={Karim Belhadj and F. Moncada Reyes and Jean-Pierre Farcet and Herv{\'e} Tilly and Christian Bastard and R{\'e}gis Angonin and Eric Deconinck and Fr{\'e}d{\'e}ric Charlotte and V{\'e}ronique Leblond and Eric Labouyrie and Pierre Lederlin and Jean-François Emile and B{\'e}atrice Delmas-Marsalet and Bertrand Arnulf and E Zafrani and PH. Gaulard},
  journal={Blood},
  year={2003},
  volume={102 13},
  pages={
          4261-9
        }
}
We report on the characteristics of 21 patients with hepatosplenic gammadelta T-cell lymphoma (HSgammadeltaTCL), an entity recognized since 1994 in the Revised European American Lymphoma (REAL) classification. Median age was 34 years. Patients had splenomegaly (n = 21), hepatomegaly (n = 15), and thrombocytopenia (n = 20). Histopathologic findings were homogeneous and showed the presence of medium-sized lymphoma cells within the sinusoids of splenic red pulp, liver, and bone marrow. Marrow… CONTINUE READING
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