Hepatoprotective role and antioxidant capacity of selenium on arsenic-induced liver injury in rats.

@article{Messarah2012HepatoprotectiveRA,
  title={Hepatoprotective role and antioxidant capacity of selenium on arsenic-induced liver injury in rats.},
  author={Mahfoud Messarah and Fahima Klibet and Amel Boumendjel and Cherif Abdennour and Noureddine Bouzerna and Mohamed Salah Boulakoud and Abdelfatteh El feki},
  journal={Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie},
  year={2012},
  volume={64 3},
  pages={167-74}
}
The present study was undertaken to evaluate the protective effect of selenium against arsenic-induced oxidative damage in experimental rats. Males were randomly divided into four groups where the first was served as a control, whereas the remaining groups were respectively treated with sodium selenite (3 mg/kg b.w.), sodium arsenite (5.55 mg/kg b.w.) and a combination of sodium arsenite and sodium selenite. Changes in liver enzyme activities, thiobarbituric acid reactive substances (TBARS… CONTINUE READING

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