Hepatoprotective effects of simvastatin on paracetamol -induced hepatic damage in rats

  • Mahdi M. Thwaini, Hanaa S. Kadhem, Thi Qar
  • Published 2015


This study was designed to investigate the possibility of statins hepatoprotection in paracetamol toxicicity. Paracetamol hepatotoxicity was associated with significant decrease in the serum total albumin(g/dl) p< 0.05) and total protein(g/dl) ( p< 0.05) . However, it significantly increased ( p< 0.0001), ALT IU/L, AST IU/L, and ALP IU/L as shown in group 3… (More)


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