Hepatoprotective constituents of the edible brown alga Ecklonia stolonifera on tacrine-induced cytotoxicity in Hep G2 cells.

@article{Kim2005HepatoprotectiveCO,
  title={Hepatoprotective constituents of the edible brown alga Ecklonia stolonifera on tacrine-induced cytotoxicity in Hep G2 cells.},
  author={Youn Chul Kim and Ren Bo An and Na Young Yoon and Taek-Jeong Nam and Jae Sue Choi},
  journal={Archives of pharmacal research},
  year={2005},
  volume={28 12},
  pages={1376-80}
}
In this study, ethanolic extracts from 18 seaweed variants were assessed for hepatoprotective activity against tacrine-induced cytotoxicity in Hep G2 cells. Only one of these, Ecklonia stolonifera Okamura (Laminariaceae), a member of the brown algae, exhibited promising hepatoprotective activity. Bioassay-guided fractionation of the active ethyl acetate (EtOAc) soluble fraction obtained from the ethanolic extract of E. stolonifera, resulted in the isolation of several phlorotannins… CONTINUE READING

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