Hepatoprotective and free radical scavenging activities of prenylflavonoids, coumarin, and stilbene from Morus alba.

@article{Oh2002HepatoprotectiveAF,
  title={Hepatoprotective and free radical scavenging activities of prenylflavonoids, coumarin, and stilbene from Morus alba.},
  author={Hyuncheol Oh and Eun-Kyung Ko and Jung-Yang Jun and Myung-Hoon Oh and Sung-Uk Park and Ki-Hong Kang and H S Lee and Youn Chul Kim},
  journal={Planta medica},
  year={2002},
  volume={68 10},
  pages={932-4}
}
Chemical investigation of the EtOH extract of Morus alba L. (Moraceae), as guided by free radical scavenging activity, furnished 5,7-dihydroxycoumarin 7-methyl ether (1), two prenylflavones, cudraflavone B (2) and cudraflavone C (3), and oxyresveratrol (4). Compounds 1 and 4 showed superoxide scavenging effects with the IC(50) values of 19.1 +/- 3.6 and 3.81 +/- 0.5 microM, respectively. Compound 4 exhibited a DPPH free radical scavenging effect (IC(50) = 23.4 +/- 1.5 microM). Compounds 2 and 4… CONTINUE READING

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