• Medicine
  • Published in
    Indian journal of…
    2009

Hepatoprotective activity of six polyherbal formulations in CCl4-induced liver toxicity in mice.

@article{Girish2009HepatoprotectiveAO,
  title={Hepatoprotective activity of six polyherbal formulations in CCl4-induced liver toxicity in mice.},
  author={Chandrashekaran Girish and Bidhan Chandra Koner and S. Jayanthi and K Ramachandra Rao and Bhargavan Rajesh and Suresh Chandra Pradhan},
  journal={Indian journal of experimental biology},
  year={2009},
  volume={47 4},
  pages={
          257-63
        }
}
To evaluate pretreatment of six polyherbal liquid formulations (PLFs) commercially available in India, on CCl4-induced liver injury, Swiss albino mice were treated for 7 days with distilled water or PLFs (2.6 and 5.2 ml/kg body weight/day, po) followed by single sc injection of 50% (v/v) CCl4 in arachis oil at a dose of 1 ml/kg. The serum biochemical parameters such as alanine transaminases, aspartate transaminases and alkaline phosphatase were estimated. Phenobarbitone-induced sleeping time… CONTINUE READING

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