• Corpus ID: 55502336

Hepatoprotective activity of fruit extract of Garcinia pedunculata BJP

@inproceedings{Mundugaru2017HepatoprotectiveAO,
  title={Hepatoprotective activity of fruit extract of Garcinia pedunculata BJP},
  author={Ravi Mundugaru and Madhan Chakkravarthy Varadharajan and Ravishankar Basavaiah},
  year={2017}
}
The objective of this study is to explore the hepatoprotective activity of fruits of Garcinia pedunculata in paracetamol-induced liver toxicity in rats. Paracetamol-induced hepatotoxicity was evaluated by an increase in serum transaminases and alkaline phosphatase activity. Histopathological observation showed extensive disturbance in the liver cytoarchitecture in comparison to normal control liver sections. Pre-treatment with aqueous extract of fruits of G. pedunculata prevented the… 
1 Citations

Figures and Tables from this paper

Protective Effect of Cynodon dactylon Aqueous Extract in Streptozotocin Diabetes Induced Liver Damage in Rats – Histological
TLDR
The observed histopathological changes correlated with the biochemical results, confirmed the protective effect of liver tissue in streptozotocin diabetes induced liver damage in Wistar rats.

References

SHOWING 1-10 OF 16 REFERENCES
Hepatoprotection by Elephantopus scaber Linn. in CCl4-induced liver injury.
  • M. Rajesh, M. Latha
  • Biology, Chemistry
    Indian journal of physiology and pharmacology
  • 2001
TLDR
The biochemical changes induced by CCI4 in different tissues particularly in the liver tissue improved following treatment with E. scaber Linn, suggesting the hepatoprotective effect of this medicinal plant.
Ethnomedicinal plants used for gastro-intestinal diseases by Adi tribes of Dehang-Debang Biosphere Reserve in Arunachal Pradesh.
An ethno-medico-botanical survey was carried out in Adi dominated areas of Dehang-Debang Biosphere Reserve (DDBR) of Arunachal Pradesh during 2005-2007 to study the pattern of use, preparation, and
Experimental paracetamol‐induced hepatic necrosis: A histopathological study
TLDR
The main objective of the present study was to provide information by examining the changes in the livers of rats killed at various intervals after administration of a single large dose of paracetamol.
Wild edible plants of Majuli island and Darrang districts of Assam
The Northeastern region of India is divided into three divisions, namely Meghalaya plateau, the Northeastern hills and basin, and the Brahmaputra valley, where Brahmaputra valley is the largest river
The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings
TLDR
The result is that paracetamol does not suppress the severe inflammation of rheumatoid arthritis and acute gout but does inhibit the lesser inflammation resulting from extraction of teeth and is also active in a variety of inflammatory tests in experimental animals.
Pathogenesis and Mechanisms of Liver Cell Necrosis
Acetaminophen poisoning and toxicity.
TLDR
Although toxicity and fatalities have occurred in the adolescent age group, only one death in younger children has been recorded and the question must be raised as to how many cases of "jaundice of unknown etiology" are actually due to this drug.
Acetaminophen‐induced acute liver failure: Results of a United States multicenter, prospective study
TLDR
In conclusion, acetaminophen hepatotoxicity far exceeds other causes of acute liver failure in the United States, and education of patients, physicians, and pharmacies to limit high‐risk use settings is recommended.
Polyisoprenylated benzophenones from Garcinia pedunculata
...
...