Hepatoma-derived growth factor-related protein-3 interacts with microtubules and promotes neurite outgrowth in mouse cortical neurons.

@article{ElTahir2009HepatomaderivedGF,
  title={Hepatoma-derived growth factor-related protein-3 interacts with microtubules and promotes neurite outgrowth in mouse cortical neurons.},
  author={Heba Mahmoud El-Tahir and Mekky Mohamed Abouzied and Rainer Gallitzendoerfer and Volkmar Gieselmann and Sebastian Franken},
  journal={The Journal of biological chemistry},
  year={2009},
  volume={284 17},
  pages={11637-51}
}
Hepatoma-derived growth factor-related proteins (HRP) comprise a family of 6 members, which the biological functions are still largely unclear. Here we show that during embryogenesis HRP-3 is strongly expressed in the developing nervous system. At early stages of development HRP-3 is located in the cytoplasm and neurites of cortical neurons. Upon maturation HRP-3 relocalizes continuously to the nuclei and in the majority of neurons of adult mice it is located exclusively in the nucleus. This… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-2 of 2 references

Modulates Microtubules 11650 JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME

  • P. Opal, J. J. Garcia, F. Propst, A. Matilla, H. T. Orr, H. Y. Zoghbi
  • APRIL 24,
  • 2009
1 Excerpt

NUMBER 17 JOURNAL OF BIOLOGICAL CHEMISTRY 11651 by gest on A ril 26, 2016 hp://w w w .jb.org/ D

  • Mekky M. Abouzied, Rainer Gallitzendoerfer, Volkmar
  • Surg. Oncol
  • 2006

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