Hepatolithiasis associated with cholangiocarcinoma

  title={Hepatolithiasis associated with cholangiocarcinoma},
  author={C H Su and Yi-Ming Shyr and Wing-yiu Lui and F K P'eng},
  journal={British Journal of Surgery},
Background Intrahepatic stone is common in East Asia. Hepatolithiasis is a risk factor for cholangiocarcinoma but it is difficult to make an accurate diagnosis before operation. The effect of intrahepatic stone on diagnosis, treatment and survival in patients with coexistent cholangiocarcinoma was investigated. 

Intrahepatic cholangiocarcinoma and hepatolithiasis: an unusual association in Western countries.

The association of hepatolithiasis and a cholangiocarcinoma in a Caucasian patient with a 17-year history of recurrent pancreatitis associated with hepatolithia is reported.

Intrahepatic stones might mimic cholangiocarcinoma on ERCP.

This is a report of a case of intrahepatic stones with no such underlying abnormalities and which caused misleading cholangiographic appearances.

[Hepaticolithiasis. Rare benign disease of the intrahepatic bile ducts].

A case of hepaticolithiasis and concurrent pancreatic metaplasia is shown, which is a rare disease of the intrahepatic bile ducts endemic to east Asia and also is known as oriental cholangiohepatitis.

Pyogenic liver abscess related to intrahepatic bile duct stones: Difficulties in infectious control and diagnosis of concomitant cholangiocarcinoma

Cholangitis, bacteremia, and pyogenic liver abscess (PLA) can be often caused by intrahepatic bile ducts stone (IBDS), which is endemic to South‐East Asia. The association between IBDS and

CT findings of cholangiocarcinoma associated with recurrent pyogenic cholangitis.

Cholangiocarcinoma associated with recurrent pyogenic cholangitis is predominantly located in the atrophic hepatic lobes and in the hepatic lobe of biliary calculi and is associated with the narrowing or obliteration of the portal vein.

Imaging of perihilar cholangiocarcinoma.

Imaging plays a central role in the detection, differential diagnosis, and staging of perihilar cholangiocarcinoma.

A Case of Intrahepatic Cholangiocarcinoma Associated with Hepatolithiasis

Under the diagnosis of intrahepatic cholangiocarcinoma associated with hepatolithiasis, the patient was conducted left hepatic lobectomy with bile duct resection and right hepaticojejunostomy with no evidence of recurrent disease during 1-year follow-up.

Recurrent Pyogenic Cholangitis

Recurrent pyogenic cholangitis (RPC) is an inflammatory condition of the liver and biliary tree characterized by recurrent attacks of cholangitis associated with dilation and stricturing of the



A reappraisal of cholangiocarcinoma in patient with hepatolithiasis

During the past 3 years, an increased incidence of patients with hepatolithiasis associated with cholangiocarcinoma was noted.

Cholangiocarcinoma as related to chronic intrahepatic cholangitis and hepatolithiasis. Case report and review of the literature.

The possible pathogenesis of cholangiocarcinomas is discussed and the importance of endoscopic retrograde cholANGiography in the diagnosis of this malignancy is emphasized.

Hepatolithiasis associated with cholangiocarcinoma. Possible etiologic significance

Three cases of primary bile duct carcinomas (cholangiocarcinomas) were found among 61 cases of hepatolithiasis, and hyperplasia of the columnar cells was often present.

Cholangiocarcinoma in Hepatolithiasis

The authors' observations suggest that whenever intrahepatic stones are encountered in patients over 50 years of age with a long history of recurrent cholangitis and intractable pain, further examination incuding echo-guided aspiration cytology, liver scanning, and peritoneoscopy should be performed to rule out a coexisting Cholangiocarcinoma.

Intrahepatic cholangiocarcinoma in hepatolithiasis: A frequently overlooked disease

Five cases of intrahepatic cholangiocarcinoma were found among 101 cases of hepatolithiasis, and an intraoperative frozen‐section examination should be considered under the following circumstances: whitish nodular mass over liver, mucinous substance within bile duct, and enlarged, firm lymph nodes clustered along the hepatic arteries and/or celiac arteries.

Intrahepatic stones associated with cholangiocarcinoma.

It became apparent that early diagnosis can be obtained from the following: detection of a hyperechoic mass in the liver parenchyma during abdominal ultrasonography, a scintigraphic defect near the hilum, and intraoperative choledochoscopic findings which showed an intraluminal tumor or infiltrative lesion.

Clinical experience in 20 hepatic resections for peripheral cholangiocarcinoma

During the 10‐year period from 1978 to 1987, hepatic resections were performed on 20 patients with peripheral cholangiocarcinoma (PCC), with average age, 48.5 years, and the overall mean survival time was 20.5 months.

Mucosal dysplasia of the liver and the intraductal variant of peripheral cholangiocarcinoma in hepatholithiasis

The authors hypothesize that the lining epithelium of the large bile duct, when persistently exposed to biochemically altered bile, may undergo a carcinomatous transformation through a stage of mucosal dysplasia.

Intrahepatic stones associated with cholangiocarcinoma.

教室例を含めて文献上報告されている肝内胆管癌 (CC) 合併肝内結石症 (IHS) の90例を集計し臨床病理学的に検討した.その結果は,(1) CCの合併はIHS全体の1.5~9.4%を占めた.(2) CC合併IHSは男性に多くみられた.(3) 一般に40歳以上にみられ, 60歳代に最も発生頻度が高かった.(4) 20年以上にわたる病悩期間を有する症例が36%を占めた.(5)