Hepatocyte polarity.

  title={Hepatocyte polarity.},
  author={Aleksandr Treyer and Anne M{\"u}sch},
  journal={Comprehensive Physiology},
  volume={3 1},
Hepatocytes, like other epithelia, are situated at the interface between the organism's exterior and the underlying internal milieu and organize the vectorial exchange of macromolecules between these two spaces. To mediate this function, epithelial cells, including hepatocytes, are polarized with distinct luminal domains that are separated by tight junctions from lateral domains engaged in cell-cell adhesion and from basal domains that interact with the underlying extracellular matrix. Despite… CONTINUE READING
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