Hepatocyte growth factor stimulates root growth during the development of mouse molar teeth.

@article{Sakuraba2012HepatocyteGF,
  title={Hepatocyte growth factor stimulates root growth during the development of mouse molar teeth.},
  author={Hirotake Sakuraba and Naoki Fujiwara and A Sasaki-Oikawa and Masahiro Sakano and Yashuhiko Tabata and Keishi Otsu and Kiyoto Ishizeki and Hidemitsu Harada},
  journal={Journal of periodontal research},
  year={2012},
  volume={47 1},
  pages={81-8}
}
BACKGROUND AND OBJECTIVE It is well known that tooth root formation is initiated by the development of Hertwig's epithelial root sheath (HERS). However, relatively little is known about the regulatory mechanisms involved in root development. As hepatocyte growth factor (HGF) is one of the mediators of epithelial-mesenchymal interactions in rodent tooth, the objective of this study was to examine the effects of HGF on the root development of mouse molars. MATERIAL AND METHODS The HERS of mouse… CONTINUE READING

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