Hepatocyte growth factor is a mitogen for alveolar type II cells in rat lavage fluid.

@article{Mason1996HepatocyteGF,
  title={Hepatocyte growth factor is a mitogen for alveolar type II cells in rat lavage fluid.},
  author={Robert J. Mason and Kathleen McCormick-Shannon and Jeffrey S. Rubin and Toshikazu Nakamura and Christina C. Leslie},
  journal={The American journal of physiology},
  year={1996},
  volume={271 1 Pt 1},
  pages={L46-53}
}
Proliferation of type II cells is required for maintenance of the alveolar epithelium and for restoration after lung injury. Although various known growth factors have been reported to stimulate type II cell proliferation in vitro, there is very little knowledge on which growth factors are present in the lung in vivo. We have previously reported that rat lavage fluid contains a mitogen(s) for type II cells, and this study was de signed to identify the growth factor(s) in this biological fluid… CONTINUE READING
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