Hepatocyte growth factor facilitates colonic mucosal repair in experimental ulcerative colitis in rats.

Abstract

Hepatocyte growth factor (HGF) modulates intestinal epithelial cell proliferation and migration, serving as a critical regulator of intestinal wound healing. In this study, we examined the effect of administration of recombinant human HGF on colonic mucosal damage in vivo. Acute colitis was induced in rats by feeding with 5% dextran sulfate sodium (DSS) for… (More)

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@article{Tahara2003HepatocyteGF, title={Hepatocyte growth factor facilitates colonic mucosal repair in experimental ulcerative colitis in rats.}, author={Yoshihiro Tahara and Akio Ido and Shojiro Yamamoto and Yoshifumi Miyata and Hirofumi Uto and Takeshi Hori and Katsuhiro Hayashi and Hirohito Tsubouchi}, journal={The Journal of pharmacology and experimental therapeutics}, year={2003}, volume={307 1}, pages={146-51} }