Hepatocyte growth factor enhances the invasion activity of human hepatocellular carcinoma cell lines.

Abstract

We investigated whether hepatocyte growth factor (HGF) enhances the invasion activity of three human HCC cell lines, HLF, HLE, and HC-4, in vitro. The analysis of the invasiveness consisted of the production of u-PA and the chemotaxis for fibronectin. Invasion activity of all cell lines was enhanced by the addition of recombinant human hepatocyte growth… (More)

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@article{Kamiyama1998HepatocyteGF, title={Hepatocyte growth factor enhances the invasion activity of human hepatocellular carcinoma cell lines.}, author={Toshiya Kamiyama and Yumi Une and Junichi Uchino and J-i Hamada}, journal={International journal of oncology}, year={1998}, volume={12 3}, pages={655-9} }