Hepatocyte growth factor activates tumor stromal fibroblasts to promote tumorigenesis in gastric cancer.

Abstract

Cancer-associated fibroblasts (CAFs), as the activated fibroblasts in tumor stroma, are important modifiers of tumor progression. However, the mechanisms underlying stromal fibroblast activation and their promotion of tumor growth remain largely unknown in gastric cancer. Here, we show that normal fibroblasts (NFs) from non-cancerous regions of gastric… (More)
DOI: 10.1016/j.canlet.2013.02.002

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Cite this paper

@article{Wu2013HepatocyteGF, title={Hepatocyte growth factor activates tumor stromal fibroblasts to promote tumorigenesis in gastric cancer.}, author={Xiongyan Wu and Xuehua Chen and Quan Zhou and Pu Li and Beiqin Yu and Jianfang Li and Ying Qu and Jun Yan and Yingyan Yu and Min Yan and Zheng-gang Zhu and Bing-ya Liu and Liping Su}, journal={Cancer letters}, year={2013}, volume={335 1}, pages={128-35} }