Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats.

@article{Miller1994HepatocyteGF,
  title={Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats.},
  author={Steven B. Miller and Daniel Rodr{\'i}guez Mart{\'i}n and John M. Kissane and Marc R. Hammerman},
  journal={The American journal of physiology},
  year={1994},
  volume={266 1 Pt 2},
  pages={F129-34}
}
Effects of hepatocyte growth factor (HGF) administration were examined in a model of acute ischemic renal injury induced by bilateral renal artery occlusion in rats. Compared with rats administered vehicle, rats administered 20 micrograms HGF subcutaneously 30 min postischemia had significantly lower serum creatinine and blood urea nitrogen levels over the course of 7 days postocclusion, enhanced insulin clearances measured on day 2 postocclusion, reduced mortality, and much less injury evident… CONTINUE READING

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