Hepatocellular carcinoma with an unusual neuroendocrine component.

@article{Yamaguchi2004HepatocellularCW,
  title={Hepatocellular carcinoma with an unusual neuroendocrine component.},
  author={Rin Yamaguchi and Osamu Nakashima and Toshiro Ogata and Keiichiro Hanada and Tsutomu Kumabe and Masamichi Kojiro},
  journal={Pathology international},
  year={2004},
  volume={54 11},
  pages={861-5}
}
We report a rare case of hepatocellular carcinoma (HCC) with an unusual neuroendocrine component. During a follow-up study for chronic hepatitis C in a 71-year-old man, a nodular lesion showed rapid growth from 1 cm to 4 cm in diameter within 3 months. Histologically, the tumor was consistent with moderately differentiated HCC, but was intermingled with nests of small round cells with scarce cytoplasm, which resembled those found in small cell carcinoma. This population formed small solid nests… CONTINUE READING