Hepatocellular carcinoma producing a granulocyte colony-stimulating factor: report of a resected case with a literature review.

@article{Araki2007HepatocellularCP,
  title={Hepatocellular carcinoma producing a granulocyte colony-stimulating factor: report of a resected case with a literature review.},
  author={Ken-ichiro Araki and Fumiaki Kishihara and Ken Takahashi and Takashi Matsumata and Tatsuo Shimura and Taketoshi Suehiro and Hiroyuki Kuwano},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2007},
  volume={27 5},
  pages={716-21}
}
A complete resection of a hepatocellular carcinoma (HCC) producing the granulocyte colony-stimulating factor (G-CSF) was performed and is reported here. The patient had a few general symptoms and complications, such as the paraneoplastic syndrome. He had marked granulocytosis, and his serum levels of G-CSF and interleukin-6 were elevated. The pathological findings of the resected specimen revealed poorly differentiated HCC with sarcomatous change and showed, immunohistochemically, staining of G… CONTINUE READING

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