Hepatocellular carcinoma in ground squirrels persistently infected with ground squirrel hepatitis virus.

@article{Marion1986HepatocellularCI,
  title={Hepatocellular carcinoma in ground squirrels persistently infected with ground squirrel hepatitis virus.},
  author={Patricia L. Marion and M J Van Davelaar and S S Knight and Felix H Salazar and Gabriel Carvalho Garcia and Hans Popper and William S. Robinson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1986},
  volume={83 12},
  pages={4543-6}
}
Although persistent infection with hepatitis B virus and woodchuck hepatitis virus has been associated with development of hepatocellular carcinoma in the host, little has been known of such an association with ground squirrel hepatitis virus (GSHV), which is closely related to the woodchuck virus. Colonies of GSHV-infected and -uninfected Beechey ground squirrels were observed for tumors for a period of 5 years. Tumors developed in seven squirrels after a minimum of 2.4 years of observation… CONTINUE READING

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