Hepatocellular carcinoma: IL28B polymorphism involved in HCV-related carcinogenesis

  • Published 2012 in Nature Reviews Gastroenterology &Hepatology


This study indicates that liver progenitor cell markers are upregulated in patients with alcoholic hepatitis. Notably, EpCAM, Prominin1 and Keratin7 expression was significantly increased in alcoholic hepatitis compared with in normal livers, chronic hepatitis C or HCV-induced cirrhosis. Keratin7 expression also correlated with disease severity, and Keratin7 and Prominin1 (but not EpCAM) could independently predict mortality at 90 days.

DOI: 10.1038/nrgastro.2012.7

Cite this paper

@article{2012HepatocellularCI, title={Hepatocellular carcinoma: IL28B polymorphism involved in HCV-related carcinogenesis}, author={}, journal={Nature Reviews Gastroenterology &Hepatology}, year={2012}, volume={9}, pages={124-124} }