Hepatocellular carcinoma HepG2 cell apoptosis and caspase-8 and Bcl-2 expression induced by injectable seed extract of Coix lacryma-jobi.

@article{Lu2011HepatocellularCH,
  title={Hepatocellular carcinoma HepG2 cell apoptosis and caspase-8 and Bcl-2 expression induced by injectable seed extract of Coix lacryma-jobi.},
  author={Yun Lu and Bing-yuan Zhang and Zhuo-Xia Jia and Wen-Jin Wu and Zheng-Qiao Lu},
  journal={Hepatobiliary & pancreatic diseases international : HBPD INT},
  year={2011},
  volume={10 3},
  pages={303-7}
}
BACKGROUND Many Chinese herbs, especially herbal injections, have been shown to have anti-tumor effects in recent years. However, since most reports focus on the clinical effectiveness of these herbs, their mechanisms of action are not well understood. In this study, we assessed apoptosis in the hepatocellular carcinoma (HCC) cell line HepG2 induced by an injectable extract from the seed of Coix lacryma-jobi (Semen coicis, SC), and monitored the expression of Bcl-2 and caspase-8. METHODS… CONTINUE READING
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