Hepatocellular Carcinoma in Transplantable Child-Pugh A Cirrhotics: Should Cost Affect Resection vs Transplantation?

@article{Michelakos2018HepatocellularCI,
  title={Hepatocellular Carcinoma in Transplantable Child-Pugh A Cirrhotics: Should Cost Affect Resection vs Transplantation?},
  author={T. Michelakos and Dimitrios Xourafas and Motaz Qadan and Rafael V. Pieretti-Vanmarcke and Lei Cai and Madhukar S. Patel and Joel T Adler and Fermin Fontan and Usama Basit and Parsia A. Vagefi and Nahel Elias and Kenneth K Tanabe and David H. Berger and Heidi Yeh and James F. Markmann and David C. Chang and Cristina R. Ferrone},
  journal={Journal of Gastrointestinal Surgery},
  year={2018},
  volume={23},
  pages={1135-1142}
}
BackgroundThere is no consensus regarding the optimal surgical treatment for transplantable hepatocellular carcinoma (HCC) patients with well-compensated cirrhosis. Our aim was to compare outcomes between Child-Pugh A (CPA) cirrhotics who underwent liver resection or transplantation for HCC.MethodsClinicopathologic data were retrospectively collected for all surgically treated HCC patients between 7/1992 and 12/2015. Disease-free survival (DFS) and overall survival (OS) were calculated from the… 

Poorly differentiated hepatocellular carcinoma: resection is equivalent to transplantation in patients with low liver fibrosis.

  • O. SalehiE. Vega C. Conrad
  • Medicine
    HPB : the official journal of the International Hepato Pancreato Biliary Association
  • 2021

The Treatment Effect of Liver Transplantation versus Liver Resection for HCC: A Review and Future Perspectives

TLDR
A comprehensive review of research articles comparing these two treatments with a focus on factors accounting for selection bias is presented and a new research design is suggested that uses a treatment guideline to help ensure that the groups are more comparable.

Conditional Survival in Resected Pancreatic Ductal Adenocarcinoma Patients Treated with Total Neoadjuvant Therapy

TLDR
For resected TNT-treated BR/LA PDAC patients, the probability of surviving an additional length of time increases as a function of survival already accrued and dynamic survival estimates may allow personalized follow-up and counseling.

Liver resection versus liver transplantation for hepatocellular carcinoma within Milan criteria: a meta-analysis of 18,421 patients.

TLDR
Mortality after LR for HCC is nearly 50% higher compared to LT and the risk of recurrence after LR is threefold that of LT, and survival between LR and LT were similar in uninodular disease.

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