Hepatobiliary transport of IgA in the golden Syrian hamster (Mesocricetus auratus).

Abstract

Do hamsters, like rats, rabbits and mice, possess an hepatocyte 'IgA pump' whereby circulating plasma polymeric IgA (pIgA) is actively transported into bile, against a concentration gradient, via the polymeric Ig receptor or secretory component (SC)? Precipitating antisera, raised against rat Igs and serum proteins, and crossreacting with their hamster… (More)

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