Xanthoascin (1-4(hydroxyphenyl)-4-(2,2-dimethyl-6-chromanyl)-2,3-diisocyano-1,3-butadiene), a toxic metabolite recently isolated from rice grains infested with Aspergillus candidus L., caused acute hepatic injury with jaundice in mice. Following this, if the animals survived, degeneration of the myocardium developed over several weeks. Myocardial cells of… (More)
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