Hepatitis C virus virology and new treatment targets

  title={Hepatitis C virus virology and new treatment targets},
  author={V. Meier and G. Ramadori},
  journal={Expert Review of Anti-infective Therapy},
  pages={329 - 350}
  • V. Meier, G. Ramadori
  • Published 2009
  • Medicine
  • Expert Review of Anti-infective Therapy
  • Hepatitis C virus (HCV) infection is the leading cause of chronic liver disease. An estimated 130 million people worldwide are persistently infected with HCV. Almost half of patients who have chronic HCV infection cannot be cured with the standard treatment consisting of pegylated IFN-α and ribavirin. For those patients who do not respond to this standard antiviral therapy, there is currently no approved treatment option available. Recent progress in structure determination of HCV proteins and… CONTINUE READING
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