Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus.

@article{Jones2007HepatitisCV,
  title={Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus.},
  author={Christopher Tyler Jones and Catherine L. Murray and Dawnnica K Eastman and Jodie A Tassello and Charles M. Rice},
  journal={Journal of virology},
  year={2007},
  volume={81 16},
  pages={8374-83}
}
Hepatitis C virus (HCV) infection is a global health concern affecting an estimated 3% of the world's population. Recently, cell culture systems have been established, allowing recapitulation of the complete virus life cycle for the first time. Since the HCV proteins p7 and NS2 are not predicted to be major components of the virion, nor are they required for RNA replication, we investigated whether they might have other roles in the viral life cycle. Here we utilize the recently described… CONTINUE READING
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