Hepatitis C virus molecular evolution: transmission, disease progression and antiviral therapy.

@article{Preciado2014HepatitisCV,
  title={Hepatitis C virus molecular evolution: transmission, disease progression and antiviral therapy.},
  author={Mar{\'i}a Victoria Preciado and Pamela Valva and Alejandro Escobar-Guti{\'e}rrez and Paula Rahal and Karina Ru{\'i}z-Tovar and Lilian H T Yamasaki and Carlos Arturo V{\'a}zquez-Chac{\'o}n and Armando Mart{\'i}nez-Guarneros and Juan Carlos Carpio-Pedroza and Salvador Fonseca-Coronado and Mayra Cruz-Rivera},
  journal={World journal of gastroenterology},
  year={2014},
  volume={20 43},
  pages={
          15992-6013
        }
}
Hepatitis C virus (HCV) infection represents an important public health problem worldwide. Reduction of HCV morbidity and mortality is a current challenge owned to several viral and host factors. Virus molecular evolution plays an important role in HCV transmission, disease progression and therapy outcome. The high degree of genetic heterogeneity characteristic of HCV is a key element for the rapid adaptation of the intrahost viral population to different selection pressures (e.g., host immune… Expand
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