Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1.

Abstract

BACKGROUND AND AIMS Hepatitis C virus (HCV)-induced chronic inflammation may induce oxidative stress which could compromise the repair of damaged DNA, rendering cells more susceptible to spontaneous or mutagen-induced alterations, the underlying cause of liver cirrhosis and hepatocellular carcinoma. In the current study we examined the induction of reactive… (More)
DOI: 10.1111/j.1440-1746.2009.06128.x

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@article{Pal2010HepatitisCV, title={Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1.}, author={Sampa Pal and Stephen J. Polyak and Nazneen Bano and Wan Chong Qiu and Robert L. Carithers and Margaret C. Shuhart and David R. Gretch and Aditi Das}, journal={Journal of gastroenterology and hepatology}, year={2010}, volume={25 3}, pages={627-34} }