Hepatitis C virus-associated glomerulonephritis. Effect of alpha-interferon therapy.

  title={Hepatitis C virus-associated glomerulonephritis. Effect of alpha-interferon therapy.},
  author={Richard J Johnson and David R. Gretch and William G. Couser and Charles E. Alpers and Janet P Wilson and Minjun Chung and Jaime Hart and Richard Willson},
  journal={Kidney international},
  volume={46 6},
Hepatitis C virus (HCV) infection may present as a primary glomerular disease. We report 34 adult patients who presented with proteinuria and had circulating anti-HCV antibodies. Primary risk factors included a history of intravenous drug abuse (56%) or blood transfusion (18%). Patients presented with nephrotic syndrome (71%) or with non-nephrotic proteinuria (29%) and had membranoproliferative or acute proliferative glomerulonephritis on renal biopsy. Signs of clinical liver disease were… CONTINUE READING
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