Hepatitis C virus RNA profiles in chronically infected individuals: do they relate to disease activity?

@article{Pontisso1999HepatitisCV,
  title={Hepatitis C virus RNA profiles in chronically infected individuals: do they relate to disease activity?},
  author={Patrizia Pontisso and Giorgio Bellati and Maurizia Brunetto and Liliana Chemello and Guido Colloredo and Rosa Di Stefano and Mark A Nicoletti and M G Rumi and Maria Grazia Ruvoletto and Roberta Soffredini and Lilli Mario Valenza and G. P. Colucci},
  journal={Hepatology},
  year={1999},
  volume={29 2},
  pages={585-9}
}
Fluctuations of hepatitis C virus (HCV)-RNA serum levels were monitored in a multicenter study in 76 chronic HCV carriers who had been followed longitudinally without receiving antiviral therapy to assess their relation with the course of liver disease activity. Forty-four patients had normal transaminases over more than 2 years, while 32 additional patients had fluctuating levels. Viral load was measured in serial serum samples prospectively collected for 10 to 12 months in 54 patients and in… CONTINUE READING
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