Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins.

@article{Shi2002HepatitisCV,
  title={Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins.},
  author={Stephanie T. Shi and Stephen J. Polyak and Hong Tu and Deborah R. Taylor and David R. Gretch and Michael M C Lai},
  journal={Virology},
  year={2002},
  volume={292 2},
  pages={198-210}
}
The nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) has been shown to interact with a variety of cellular proteins and implicated in the regulation of cell growth, interferon resistance, and other cellular signaling pathways, but the role of NS5A in HCV pathogenesis has not been firmly established. To further characterize this multifunctional protein, we instigated the studies of the subcellular localization of NS5A in a hepatoma cell line. NS5A was localized to the perinuclear… CONTINUE READING
108 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 108 extracted citations

Similar Papers

Loading similar papers…